Tianeptine Sodium

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What is tianeptine sodium powder?

Tianeptine, a tricyclic antidepressant, is a medication used to treat serious depression. It was discovered in the 1980s by the French Society of Medical Research.

Tianeptine is a selective serotonin reuptake enhancer with limited effects on norepinephrine and dopamine uptake, unlike other tricyclic antidepressants. It’s also a complete agonist for mu- and delta-opioid receptors, with no action on kappa-opioid receptors. Euphoria is commonly induced by selective mu-opioid agonists, which may add to TIANEPTINE’s antidepressant effect.

Many European countries sell it as Coaxil/Stablon. However, it is not accessible in the United States. But Legit Cannabinoids  can help you buy Tianeptine Sodium USA without any hassle.

Origin of tianeptine sodium powder

The French Society of Medical Research patented Tianeptine Sodium powder after it was discovered by French researchers Antoine Deslandes and Michael Spedding in the 1960s.

Tianeptine is available under the trade names Stablon, Coaxil, and Tanitol in several Asian, South American, and European nations.

Tianeptine is primarily used to treat severe depressive disorder; however, it has recently been approved for the treatment of IBS and asthma.

Tianeptine sodium powder is a tricyclic antidepressant (TCA) with a structure that is similar to amitriptyline and doxepin. On the other hand, tianeptine’s mechanism of action differs from that of other antidepressants and TCAs in general.

Tianeptine Class

Tianeptine belongs to the antidepressant drug class, which is used to treat depression in adults over the age of 18. A mood condition marked by persistent feelings of sadness, loss, or anger is known as depression. Sertraline, a selective serotonin reuptake inhibitor, is included in TIANEPTINE (SSRI).

Tianeptine Sodium Application

In HepG2 cells, sodium has been tested as a steatosis-positive inducer. The effects of tianeptine sodium powder on rats subjected to swim endurance tests have also been studied.

According to this study, in rats undergoing SET, tianeptine enhanced swimming time.

Furthermore, tianeptine raised total cholesterol and LDL while decreasing triglyceride levels. As a result, tianeptine might have a role in developing metabolic syndrome.

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Medicinal Benefits of Tianeptine Sodium

Tianeptine is an antidepressant that is used to treat depression.

Tianeptine includes Tianeptine, a chemical messenger in the brain that helps regulate mood and prevent depression by affecting particular chemical messengers (serotonin, norepinephrine) that communicate between brain cells. Improving mood, cognition, and memory requires increasing the release of the serotonin hormone in the body.

Storage of Tianeptine Sodium

Place in a dark, dry, and cool place away from direct sunlight.

In Vitro Use Guide

Tianeptine was discovered to be an effective mu-opioid receptor agonist (Ki of 383+/-183 nM and EC50 of 194+/-70 nM) using radioligand binding and cell-based functional assays, including bioluminescence resonance energy transfer-based assays for G-protein activation and cAMP buildup.

Tianeptine was likewise a complete delta-opioid receptor agonist, albeit with substantially lesser efficacy (EC50 for G-protein activation of 37.4+/-11.2 uM). On the other hand, Tianeptine had no effect on the kappa-opioid receptor.

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